mouse DIS3L shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dis3l.
shAAV-257197
AAV-m-DIS3L-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dis3l (DIS3 like exosome 3′-5′ exoribonuclease). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AV340375
Description (Vector)
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Gene ID
213550
Gene Name (Vector)
DIS3 like exosome 3'-5' exoribonuclease
Gene Symbol
Dis3l
ORF Size (aa)
2913
ORF Size (bp)
2913 bp
RefSeq ID
NM_001001295
RefSeq Synonyms
NM_172519, NM_001177784, NM_001001295, BC056939,
Species
mouse
UniGene ID
Mm.268341
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.