rat CHCHD4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Chchd4.
shADV-293511
Ad-r-CHCHD4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Chchd4 (coiled-coil-helix-coiled-coil-helix domain containing 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Probably acts by forming a redox cycle with GFER/ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (Probable).
Gene ID
312559
Gene Name (Vector)
coiled-coil-helix-coiled-coil-helix domain containing 4
Gene Symbol
Chchd4
ORF Size (aa)
420
RefSeq ID
NM_001013431
RefSeq Synonyms
NM_001013431, BC091407,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.