rat PSME3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Psme3.
shADV-292850
Ad-r-PSME3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Psme3 (proteasome activator subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Ab2-371
Description (Vector)
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
Gene ID
287716
Gene Name (Vector)
proteasome activator subunit 3
Gene Symbol
Psme3
ORF Size (aa)
765
RefSeq ID
NM_001011894
RefSeq Synonyms
NM_001011894, BC089889,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.