rat EIF2S1 shRNA silencing Adenovirus

Name
Ad-r-EIF2S1-shRNA

Cat No
shADV-292431

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Eif2s1.

shADV-292431

Ad-r-EIF2S1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Eif2s1 (eukaryotic translation initiation factor 2 subunit 1 alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Gene ID

54318

Gene Name (Vector)

eukaryotic translation initiation factor 2 subunit 1 alpha

Gene Symbol

Eif2s1

ORF Size (aa)

948

ORF Size (bp)

948 bp

RefSeq ID

NM_019356

RefSeq Synonyms

NM_019356, BC087019,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.