rat S100B shRNA silencing Adenovirus

Name
Ad-r-S100B-shRNA

Cat No
shADV-292421

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat S100b.

shADV-292421

Ad-r-S100B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat S100b (S100 calcium binding protein B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

S100P

Description (Vector)

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity).

Gene ID

25742

Gene Name (Vector)

S100 calcium binding protein B

Gene Symbol

S100b

ORF Size (aa)

279

RefSeq ID

NM_013191

RefSeq Synonyms

NM_013191, BC087026,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.