rat TNFRSF1A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Tnfrsf1a.
shADV-292225
Ad-r-TNFRSF1A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Tnfrsf1a (TNF receptor superfamily member 1A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TNFR-1; Tnfr1
Description (Vector)
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Gene ID
25625
Gene Name (Vector)
TNF receptor superfamily member 1A
Gene Symbol
Tnfrsf1a
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_013091
RefSeq Synonyms
NM_013091, BC086413,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.