rat NMNAT3 shRNA silencing Adenovirus

Name 
Ad-r-NMNAT3-shRNA
Cat No 
shADV-291373
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Nmnat3.

shADV-291373
Ad-r-NMNAT3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Nmnat3 (nicotinamide nucleotide adenylyltransferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.
Gene ID
363118
Gene Name (Vector)
nicotinamide nucleotide adenylyltransferase 3
Gene Symbol
Nmnat3
ORF Size (aa)
369
ORF Size (bp)
369 bp
RefSeq ID
NM_001013224
RefSeq Synonyms
NM_001013224, BC083725,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.