rat CCL5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Ccl5.
shADV-290136
Ad-r-CCL5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ccl5 (C-C motif chemokine ligand 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Rantes; Scya5
Description (Vector)
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.
Gene ID
81780
Gene Name (Vector)
C-C motif chemokine ligand 5
Gene Symbol
Ccl5
ORF Size (aa)
279
RefSeq ID
NM_031116
RefSeq Synonyms
NM_031116, BC058138,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.