rat ATP5C1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Atp5c1.
shADV-290077
Ad-r-ATP5C1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Atp5c1 (ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Gene ID
116550
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Gene Symbol
Atp5c1
ORF Size (aa)
897
ORF Size (bp)
897 bp
RefSeq ID
NM_053825
RefSeq Synonyms
NM_053825, BC059158,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.