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mouse GDF9 shRNA silencing Adenovirus

Name 
Ad-m-GDF9-shRNA
Cat No 
shADV-281276
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Gdf9.

shADV-281276
Ad-m-GDF9-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gdf9 (growth differentiation factor 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Gdf-9
Description (Vector)
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Gene ID
14566
Gene Name (Vector)
growth differentiation factor 9
Gene Symbol
Gdf9
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
RefSeq ID
NM_008110
RefSeq Synonyms
NM_008110, BC052667,
Species
mouse
UniGene ID
Mm.9714

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.