mouse USP14 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Usp14.
shADV-281194
Ad-m-USP14-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Usp14 (ubiquitin specific peptidase 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610005K12Rik; 2610037B11Rik; AW107924; ax; C78769; nmf375
Description (Vector)
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Gene ID
59025
Gene Name (Vector)
ubiquitin specific peptidase 14
Gene Symbol
Usp14
ORF Size (aa)
1377
ORF Size (bp)
1377 bp
RefSeq ID
NM_021522
RefSeq Synonyms
NM_021522, NM_001038589, BC050197, BC005571,
Species
mouse
UniGene ID
Mm.447089
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.