mouse GJA1 shRNA silencing Adenovirus

Name 
Ad-m-GJA1-shRNA
Cat No 
shADV-280777
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Gja1.

shADV-280777
Ad-m-GJA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gja1 (gap junction protein, alpha 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AU042049; AW546267; Cnx43; connexin43; Cx43; Cx43alpha1; Gja-1; Npm1
Description (Vector)
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
Gene ID
14609
Gene Name (Vector)
gap junction protein, alpha 1
Gene Symbol
Gja1
ORF Size (aa)
1305
ORF Size (bp)
1305 bp
RefSeq ID
NM_010288
RefSeq Synonyms
NM_010288, BC055375, BC006894,
Species
mouse
UniGene ID
Mm.477216

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.