mouse CXCR3 shRNA silencing Adenovirus

Cat. No: shADV-280668

Availability: 5-8 weeks

Name: Ad-m-CXCR3-shRNA

This is an Adenovirus expressing shRNA for silencing of Mouse Cxcr3.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Species: Mouse
Gene Symbol: Cxcr3
Gene Name: chemokine (C-X-C motif) receptor 3
Gene ID: 12766
Gene Synonyms: Cd183; Cmkar3
ORF Size: 1104 bp
RefSeq#: NM_009910
Gene Description: Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC)|Function: Isoform 2 is a receptor for CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC). Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis|Function: Isoform 3 mediates the activity of CXCL11.
UniGene ID: Mm.12876