mouse ASZ1 shRNA silencing Adenovirus

Name 
Ad-m-ASZ1-shRNA
Cat No 
shADV-280558
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Asz1.

shADV-280558
Ad-m-ASZ1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Asz1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4933400N19Rik; Gasz; ORF3
Description (Vector)
Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).
Gene ID
74068
Gene Name (Vector)
ankyrin repeat, SAM and basic leucine zipper domain containing 1
Gene Symbol
Asz1
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
RefSeq ID
NM_023729
RefSeq Synonyms
NM_023729, BC058859,
Species
mouse
UniGene ID
Mm.73091

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.