mouse PRPF19 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Prpf19.
shADV-279336
Ad-m-PRPF19-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Prpf19 (pre-mRNA processing factor 19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA617263; AL024362; D19Wsu55e; NMP200; Prp19; PSO4; Snev
Description (Vector)
Plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. Binds double-stranded DNA in a sequence-nonspecific manner. Acts as a structural component of the nuclear framework. May also serve as a support for spliceosome binding and activity. Essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. May have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.
Gene ID
28000
Gene Name (Vector)
pre-mRNA processing factor 19
Gene Symbol
Prpf19
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_134129
RefSeq Synonyms
NM_134129, NM_001253844, NM_001253843, BC004070,
Species
mouse
UniGene ID
Mm.358657
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.