mouse XBP1 shRNA silencing Adenovirus

Name
Ad-m-XBP1-shRNA

Cat No
shADV-276363

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Xbp1.

shADV-276363

Ad-m-XBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Xbp1 (X-box binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

D11Ertd39e; TREB-5; TREB5; XBP-1

Description (Vector)

Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Gene ID

22433

Gene Name (Vector)

X-box binding protein 1

Gene Symbol

Xbp1

ORF Size (aa)

1071

RefSeq ID

NM_013842

RefSeq Synonyms

NM_013842, NM_001271730, BC029197, BC016079,

Species

mouse

UniGene ID

Mm.469937

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.