mouse VPS35 shRNA silencing Adenovirus

Name 
Ad-m-VPS35-shRNA
Cat No 
shADV-276059
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Vps35.

shADV-276059
Ad-m-VPS35-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Vps35 (VPS35 retromer complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI647796; Mem3
Description (Vector)
Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
Gene ID
65114
Gene Name (Vector)
VPS35 retromer complex component
Gene Symbol
Vps35
ORF Size (aa)
2391
ORF Size (bp)
2391 bp
RefSeq ID
NM_022997
RefSeq Synonyms
NM_022997, BC006637, BC005469,
Species
mouse
UniGene ID
Mm.296520

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.