mouse VDR shRNA silencing Adenovirus

Name 
Ad-m-VDR-shRNA
Cat No 
shADV-275991
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Vdr.

shADV-275991
Ad-m-VDR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Vdr (vitamin D receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Nr1i1
Description (Vector)
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
Gene ID
22337
Gene Name (Vector)
vitamin D receptor
Gene Symbol
Vdr
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_009504
RefSeq Synonyms
NM_009504, BC006716,
Species
mouse
UniGene ID
Mm.245084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.