mouse VDAC1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Vdac1.
shADV-275987
Ad-m-VDAC1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Vdac1 (voltage-dependent anion channel 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AL033343; mVDAC1; mVDAC5; Vdac5
Description (Vector)
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Gene ID
22333
Gene Name (Vector)
voltage-dependent anion channel 1
Gene Symbol
Vdac1
ORF Size (aa)
852
ORF Size (bp)
852 bp
RefSeq ID
NM_011694
RefSeq Synonyms
NM_011694, BC092257,
Species
mouse
UniGene ID
Mm.470023
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.