mouse UBE2V2 shRNA silencing Adenovirus

Name 
Ad-m-UBE2V2-shRNA
Cat No 
shADV-275506
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ube2v2.

shADV-275506
Ad-m-UBE2V2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ube2v2 (ubiquitin-conjugating enzyme E2 variant 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110021H13Rik; 4632410D19Rik; 5730524P06Rik; 6820402M05; AI848315; C81524; MMS2
Description (Vector)
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Gene ID
70620
Gene Name (Vector)
ubiquitin-conjugating enzyme E2 variant 2
Gene Symbol
Ube2v2
ORF Size (aa)
438
RefSeq ID
NM_023585
RefSeq Synonyms
NM_023585, NM_001159351, BC094903, BC083098, BC058374,
Species
mouse
UniGene ID
Mm.390775

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.