mouse UBASH3A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ubash3a.
shADV-275452
Ad-m-UBASH3A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ubash3a (ubiquitin associated and SH3 domain containing, A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5830413C03Rik; C330001M22; Sts-2; TULA; TULA-1
Description (Vector)
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Gene ID
328795
Gene Name (Vector)
ubiquitin associated and SH3 domain containing, A
Gene Symbol
Ubash3a
ORF Size (aa)
1353
ORF Size (bp)
1353 bp
RefSeq ID
NM_177823
RefSeq Synonyms
NM_177823, BC148683, BC140312,
Species
mouse
UniGene ID
Mm.387930
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.