mouse TNFRSF10B shRNA silencing Adenovirus

Name 
Ad-m-TNFRSF10B-shRNA
Cat No 
shADV-274689
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Tnfrsf10b.

shADV-274689
Ad-m-TNFRSF10B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tnfrsf10b (tumor necrosis factor receptor superfamily, member 10b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
Description (Vector)
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Gene ID
21933
Gene Name (Vector)
tumor necrosis factor receptor superfamily, member 10b
Gene Symbol
Tnfrsf10b
ORF Size (aa)
1146
ORF Size (bp)
1146 bp
RefSeq ID
NM_020275
RefSeq Synonyms
NM_020275, BC065141,
Species
mouse
UniGene ID
Mm.193430

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.