mouse TMEM188 shRNA silencing Adenovirus

Name 
Ad-m-TMEM188-shRNA
Cat No 
shADV-274480
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Cnep1r1.

shADV-274480
Ad-m-TMEM188-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cnep1r1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5033428A16Rik; NEP1-R1; Tmem188
Description (Vector)
Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.
Gene ID
382030
Gene Name (Vector)
CTD nuclear envelope phosphatase 1 regulatory subunit 1
Gene Symbol
Cnep1r1
ORF Size (aa)
378
RefSeq ID
NM_029074
RefSeq Synonyms
NM_029074, BC148291,
Species
mouse
UniGene ID
Mm.216574

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.