mouse TESC shRNA silencing Adenovirus

Name
Ad-m-TESC-shRNA

Cat No
shADV-274041

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tesc.

shADV-274041

Ad-m-TESC-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tesc (tescalcin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

1010001A17Rik; 2410011K10Rik; TE-1

Description (Vector)

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

Gene ID

57816

Gene Name (Vector)

tescalcin

Gene Symbol

Tesc

ORF Size (aa)

645

ORF Size (bp)

645 bp

RefSeq ID

NM_021344

RefSeq Synonyms

NM_021344, BC107679, BC019492,

Species

mouse

UniGene ID

Mm.273285

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.