mouse TEAD3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Tead3.
shADV-274007
Ad-m-TEAD3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tead3 (TEA domain family member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DTEF-1; ETFR-1; Tcf13r2; TEAD-3; TEF-5
Description (Vector)
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Gene ID
21678
Gene Name (Vector)
TEA domain family member 3
Gene Symbol
Tead3
ORF Size (aa)
1395
ORF Size (bp)
1395 bp
RefSeq ID
NM_011566
RefSeq Synonyms
NM_011566, NM_001204156, NM_001098226, BC156574, BC146313,
Species
mouse
UniGene ID
Mm.6655
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.