mouse SUMO2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sumo2.
shADV-273463
Ad-m-SUMO2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sumo2 (small ubiquitin-like modifier 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Smt3A; Smt3b; Smt3h2; SUMO-2
Description (Vector)
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Gene ID
170930
Gene Name (Vector)
small ubiquitin-like modifier 2
Gene Symbol
Sumo2
ORF Size (aa)
288
RefSeq ID
NM_133354
RefSeq Synonyms
NM_133354, BC095930, BC083326, BC017522,
Species
mouse
UniGene ID
Mm.29923
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.