mouse SRY shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sry.
shADV-273168
Ad-m-SRY-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sry (sex determining region of Chr Y). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Tdf; Tdy
Description (Vector)
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
Gene ID
21674
Gene Name (Vector)
sex determining region of Chr Y
Gene Symbol
Sry
ORF Size (aa)
1125
RefSeq ID
NM_011564
RefSeq Synonyms
NM_011564, BC111528,
Species
mouse
UniGene ID
Mm.377114
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.