human SRY shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SRY.
shAAV-224371
AAV-h-SRY-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SRY (sex determining region Y). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SRXX1; SRXY1; TDF; TDY
Description (Vector)
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
Gene ID
6736
Gene Name (Vector)
sex determining region Y
Gene Symbol
SRY
HGNC ID
HGNC:11311
ORF Size (aa)
615
RefSeq ID
NM_003140
RefSeq Synonyms
NM_003140, BC074924, BC074923,
Species
human
UniGene ID
Hs.1992
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.