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mouse SRA1 shRNA silencing Adenovirus

Name 
Ad-m-SRA1-shRNA
Cat No 
shADV-273113
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Sra1.

shADV-273113
Ad-m-SRA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sra1 (steroid receptor RNA activator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AA959952; Sra; Srap; Straa1; Strra1
Description (Vector)
Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
Gene ID
24068
Gene Name (Vector)
steroid receptor RNA activator 1
Gene Symbol
Sra1
ORF Size (aa)
663
ORF Size (bp)
663 bp
RefSeq ID
NM_025291
RefSeq Synonyms
NM_025291, NM_001164406, BC048362,
Species
mouse
UniGene ID
Mm.29058

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.