mouse SPIB shRNA silencing Adenovirus

Name 
Ad-m-SPIB-shRNA
Cat No 
shADV-273001
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Spib.

shADV-273001
Ad-m-SPIB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Spib (Spi-B transcription factor (Spi-1/PU.1 related)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Spi-B
Description (Vector)
Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.
Gene ID
272382
Gene Name (Vector)
Spi-B transcription factor (Spi-1/PU.1 related)
Gene Symbol
Spib
ORF Size (aa)
804
RefSeq ID
NM_019866
RefSeq Synonyms
NM_019866, BC141118,
Species
mouse
UniGene ID
Mm.8012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.