mouse SMURF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Smurf1.
shADV-272688
Ad-m-SMURF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Smurf1 (SMAD specific E3 ubiquitin protein ligase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930431E10Rik; mKIAA1625
Description (Vector)
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA.
Gene ID
75788
Gene Name (Vector)
SMAD specific E3 ubiquitin protein ligase 1
Gene Symbol
Smurf1
ORF Size (aa)
2187
ORF Size (bp)
2187 bp
RefSeq ID
NM_029438
RefSeq Synonyms
NM_029438, NM_001038627, BC029097,
Species
mouse
UniGene ID
Mm.27735
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.