mouse SIRT5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sirt5.
shADV-272011
Ad-m-SIRT5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sirt5 (sirtuin 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610012J09Rik; 1500032M05Rik; AV001953
Description (Vector)
NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
Gene ID
68346
Gene Name (Vector)
sirtuin 5
Gene Symbol
Sirt5
ORF Size (aa)
567
RefSeq ID
NM_178848
RefSeq Synonyms
NM_178848, BC087898, BC031770,
Species
mouse
UniGene ID
Mm.35325
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.