mouse SIN3A shRNA silencing Adenovirus

Name 
Ad-m-SIN3A-shRNA
Cat No 
shADV-271997
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Sin3a.

shADV-271997
Ad-m-SIN3A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sin3a (transcriptional regulator, SIN3A (yeast)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AW553200; mKIAA4126; mSin3A; Sin3
Description (Vector)
Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA (By similarity). Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
Gene ID
20466
Gene Name (Vector)
transcriptional regulator, SIN3A (yeast)
Gene Symbol
Sin3a
ORF Size (aa)
3594
ORF Size (bp)
3594 bp
RefSeq ID
NM_011378
RefSeq Synonyms
NM_011378, NM_001110351, NM_001110350, BC052716,
Species
mouse
UniGene ID
Mm.15755

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.