mouse RFC1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Rfc1.
shADV-270421
Ad-m-RFC1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Rfc1 (replication factor C (activator 1) 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
140kDa; Alp145; Recc1; RFC140
Description (Vector)
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA|Function: Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.
Gene ID
19687
Gene Name (Vector)
replication factor C (activator 1) 1
Gene Symbol
Rfc1
ORF Size (aa)
3399
ORF Size (bp)
3399 bp
RefSeq ID
NM_011258
RefSeq Synonyms
NM_011258, NM_001347358, NM_001347357, BC085173,
Species
mouse
UniGene ID
Mm.148877
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.