mouse RBMX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Rbmx.
shADV-270281
Ad-m-RBMX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Rbmx (RNA binding motif protein, X chromosome). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hnRNP G
Description (Vector)
RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways; promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.
Gene ID
19655
Gene Name (Vector)
RNA binding motif protein, X chromosome
Gene Symbol
Rbmx
ORF Size (aa)
1176
ORF Size (bp)
1176 bp
RefSeq ID
NM_011252
RefSeq Synonyms
NM_011252, NM_001166623, BC003710,
Species
mouse
UniGene ID
Mm.28275
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.