mouse PTPRR shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Ptprr

Gene Name

protein tyrosine phosphatase, receptor type, R

Gene ID

19279

Gene Synonyms

Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR

ORF Size

1971 bp

RefSeq#

NM_011217

Gene Description

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).

UniGene ID

Mm.336316