mouse PSMB4 shRNA silencing Adenovirus

Name 
Ad-m-PSMB4-shRNA
Cat No 
shADV-269637
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Psmb4.

shADV-269637
Ad-m-PSMB4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Psmb4 (proteasome (prosome, macropain) subunit, beta type 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Pros-27
Description (Vector)
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Gene ID
19172
Gene Name (Vector)
proteasome (prosome, macropain) subunit, beta type 4
Gene Symbol
Psmb4
ORF Size (aa)
795
RefSeq ID
NM_008945
RefSeq Synonyms
NM_008945, BC008241,
Species
mouse
UniGene ID
Mm.368

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.