mouse PRDX1 shRNA silencing Adenovirus

Name
Ad-m-PRDX1-shRNA

Cat No
shADV-269317

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Prdx1.

shADV-269317

Ad-m-PRDX1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Prdx1 (peroxiredoxin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

MSP23; NkefA; OSF-3; OSF3; PAG; Paga; PrdxI; prx1; PrxI; Tdpx2; TDX2; TPxA

Description (Vector)

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Gene ID

18477

Gene Name (Vector)

peroxiredoxin 1

Gene Symbol

Prdx1

ORF Size (aa)

600

RefSeq ID

NM_011034

RefSeq Synonyms

NM_011034, BC086648, BC083348,

Species

mouse

UniGene ID

Mm.30929

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.