mouse PPARA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ppara.
shADV-269120
Ad-m-PPARA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ppara (peroxisome proliferator activated receptor alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4933429D07Rik; AW742785; Nr1c1; Ppar; PPAR-alpha; PPARalpha
Description (Vector)
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Gene ID
19013
Gene Name (Vector)
peroxisome proliferator activated receptor alpha
Gene Symbol
Ppara
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
RefSeq ID
NM_011144
RefSeq Synonyms
NM_011144, NM_001113418, BC016892,
Species
mouse
UniGene ID
Mm.212789
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.