mouse PNRC2 shRNA silencing Adenovirus

Name 
Ad-m-PNRC2-shRNA
Cat No 
shADV-268982
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Pnrc2.

shADV-268982
Ad-m-PNRC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pnrc2 (proline-rich nuclear receptor coactivator 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
0610011E17Rik; D4Bwg0593e
Description (Vector)
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.
Gene ID
52830
Gene Name (Vector)
proline-rich nuclear receptor coactivator 2
Gene Symbol
Pnrc2
ORF Size (aa)
423
RefSeq ID
NM_026383
RefSeq Synonyms
NM_026383, BC006598,
Species
mouse
UniGene ID
Mm.29159

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.