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mouse PEG10 shRNA silencing Adenovirus

Name 
Ad-m-PEG10-shRNA
Cat No 
shADV-268381
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Peg10.

shADV-268381
Ad-m-PEG10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Peg10 (paternally expressed 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AA407948; Edr; HB-1; Mar2; Mart2; MEF3L; MyEF-3
Description (Vector)
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).
Gene ID
170676
Gene Name (Vector)
paternally expressed 10
Gene Symbol
Peg10
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
RefSeq ID
NM_001040611
RefSeq Synonyms
NM_130877, NM_001040611, BC156757,
Species
mouse
UniGene ID
Mm.320575

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.