mouse PACS1 shRNA silencing Adenovirus

Name 
Ad-m-PACS1-shRNA
Cat No 
shADV-267986
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Pacs1.

shADV-267986
Ad-m-PACS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pacs1 (phosphofurin acidic cluster sorting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI325977
Description (Vector)
Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN.
Gene ID
107975
Gene Name (Vector)
phosphofurin acidic cluster sorting protein 1
Gene Symbol
Pacs1
ORF Size (aa)
2886
ORF Size (bp)
2886 bp
RefSeq ID
NM_153129
RefSeq Synonyms
NM_153129, BC062886,
Species
mouse
UniGene ID
Mm.234923

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.