mouse OCA2 shRNA silencing Adenovirus

Name
Ad-m-OCA2-shRNA

Cat No
shADV-266309

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Oca2.

shADV-266309

Ad-m-OCA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Oca2 (oculocutaneous albinism II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

D7H15S12; D7Icr28RN; D7Nic1; p; p<cas>

Description (Vector)

Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color.

Gene ID

18431

Gene Name (Vector)

oculocutaneous albinism II

Gene Symbol

Oca2

ORF Size (aa)

2502

ORF Size (bp)

2502 bp

RefSeq ID

NM_021879

RefSeq Synonyms

NM_021879, BC120549, BC119220,

Species

mouse

UniGene ID

Mm.137052

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.