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mouse NXN shRNA silencing Adenovirus

Name 
Ad-m-NXN-shRNA
Cat No 
shADV-266258
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Nxn.

shADV-266258
Ad-m-NXN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nxn (nucleoredoxin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
l11Jus13
Description (Vector)
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Gene ID
18230
Gene Name (Vector)
nucleoredoxin
Gene Symbol
Nxn
ORF Size (aa)
1308
ORF Size (bp)
1308 bp
RefSeq ID
NM_008750
RefSeq Synonyms
NM_008750, BC058244, BC004688,
Species
mouse
UniGene ID
Mm.27915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.