mouse NACC1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Nacc1

Gene Name

nucleus accumbens associated 1, BEN and BTB (POZ) domain containing

Gene ID

66830

Gene Synonyms

2010001H03Rik; 4930511N13Rik; Btbd14b; Nac1

ORF Size

1545 bp

RefSeq#

NM_025788

Gene Description

Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.

UniGene ID

Mm.403815