mouse MMP16 shRNA silencing Adenovirus

Name 
Ad-m-MMP16-shRNA
Cat No 
shADV-264723
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mmp16.

shADV-264723
Ad-m-MMP16-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mmp16 (matrix metallopeptidase 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MT-MMP 3; MT3-MMP; Mt3mmp
Description (Vector)
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Gene ID
17389
Gene Name (Vector)
matrix metallopeptidase 16
Gene Symbol
Mmp16
ORF Size (aa)
1824
ORF Size (bp)
1824 bp
RefSeq ID
NM_019724
RefSeq Synonyms
NM_019724, BC057926,
Species
mouse
UniGene ID
Mm.204820

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.