mouse METTL11A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ntmt1.
shADV-264526
Ad-m-METTL11A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ntmt1 (N-terminal Xaa-Pro-Lys N-methyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610205E22Rik; AL033331; AL033332; Mettl11a; NTM1A
Description (Vector)
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
Gene ID
66617
Gene Name (Vector)
N-terminal Xaa-Pro-Lys N-methyltransferase 1
Gene Symbol
Ntmt1
ORF Size (aa)
672
ORF Size (bp)
672 bp
RefSeq ID
NM_170592
RefSeq Synonyms
NM_170592, BC027220,
Species
mouse
UniGene ID
Mm.33167
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.