mouse MAPT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mapt.
shADV-264247
Ad-m-MAPT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mapt (microtubule-associated protein tau). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI413597; AW045860; Mtapt; Tau
Description (Vector)
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Gene ID
17762
Gene Name (Vector)
microtubule-associated protein tau
Gene Symbol
Mapt
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_010838
RefSeq Synonyms
NM_010838, NM_001285456, NM_001285455, NM_001285454, NM_001038609, BC014748,
Species
mouse
UniGene ID
Mm.449812
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.