mouse MAML1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-264140
Availability:
3-5 weeks
Name:
Ad-m-MAML1-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Maml1.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Maml1
- Gene Name
- mastermind like 1 (Drosophila)
- Gene ID
- 103806
- Gene Synonyms
- AI644666; AW743257; D930008C07Rik; Mam-1; Mam1; mKIAA0200
- ORF Size
- 2364 bp
- RefSeq#
- NM_175334
- Gene Description
- Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
- UniGene ID
- Mm.51116
Related Products
Product | Cat No. |
---|---|
AAV-m-MAML1 | AAV-264140 |
Ad-m-MAML1 | ADV-264140 |
AAV-m-MAML1-shRNA | shAAV-264140 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy