mouse LIPA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Lipa.
shADV-263478
Ad-m-LIPA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lipa (lysosomal acid lipase A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA960673; Lal; Lip-1; Lip1
Description (Vector)
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Gene ID
16889
Gene Name (Vector)
lysosomal acid lipase A
Gene Symbol
Lipa
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
RefSeq ID
NM_021460
RefSeq Synonyms
NM_021460, NM_001111100, BC058564,
Species
mouse
UniGene ID
Mm.157545
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.